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Sulforaphane Inhibits Mitochondrial Permeability Transition and Oxidative Stress

Exposure of mitochondria to oxidative stress and elevated Ca(2+) promotes opening of the mitochondrial permeability transition pore (PTP), resulting in membrane depolarization, uncoupling of oxidative phosphorylation, and potentially cell death. This study tested the hypothesis that treatment of rat...

詳細記述

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書誌詳細
主要な著者: Greco, Tiffany, Shafer, Jonathan, Fiskum, Gary
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278304/
https://ncbi.nlm.nih.gov/pubmed/21986339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.09.017
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