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An alteration in concatameric structure is associated with efficient segregation of plasmids in transfected Plasmodium falciparum parasites

Transfection of the human malaria parasite Plasmodium falciparum is currently performed with circularised plasmids that are maintained episomally in parasites under drug selection but which are rapidly lost when selection pressure is removed. In this paper, we show that in instances where gene targe...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: O’Donnell, Rebecca A., Preiser, Peter R., Williamson, Donald H., Moore, Peter W., Cowman, Alan F., Crabb, Brendan S.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2001
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30406/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160894/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.3.716
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