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Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr1 gene of Plasmodium falciparum.

The pfmdr1 gene has been associated with a drug-resistant phenotype in Plasmodium falciparum, and overexpression of pfmdr1 has been associated with mefloquine- and halofantrine-resistant parasites, but little is known about the functional role of pfmdr1 in this process. Here, we demonstrate that the...

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Publicado en:Proc Natl Acad Sci U S A
Principais autores: Volkman, S K, Cowman, A F, Wirth, D F
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1995
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41079/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.19.8921
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