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Nitric oxide controls an inflammatory-like Ly6C(hi)PDCA1(+) DC subset that regulates Th1 immune responses
Using NOS2 KO mice, we investigated the hypothesis that NO modulation of BM-DC contributes to the NO-mediated control of Th1 immune responses. BM-DCs from NOS2 KO mice, compared with WT BM-DCs, have enhanced survival and responsiveness to TLR agonists, develop more Ly6C(hi)PDCA1(+) DCs that resemble...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Leukocyte Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040463/ https://ncbi.nlm.nih.gov/pubmed/21178115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0610329 |
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