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Proteasome Activators

Proteasomes degrade a multitude of protein substrates in the cytosol and nucleus, and thereby are essential for many aspects of cellular function. Because the proteolytic sites are sequestered in a closed barrel-shaped structure, activators are required to facilitate substrate access. Structural and...

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Autors principals: Stadtmueller, Beth M., Hill, Christopher P.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040445/
https://ncbi.nlm.nih.gov/pubmed/21211719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.020
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