Staphylococcus aureus Sepsis and Mitochondrial Accrual of the 8-Oxoguanine DNA Glycosylase DNA Repair Enzyme in Mice

Rationale: Damage to mitochondrial DNA (mtDNA) by the production of reactive oxygen species during inflammatory states, such as sepsis, is repaired by poorly understood mechanisms. Objectives: To test the hypothesis that the DNA repair enzyme, 8-oxoguanine DNA glycosylase (OGG1), contributes to mtDN...

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Autori principali: Bartz, Raquel R., Suliman, Hagir B., Fu, Ping, Welty-Wolf, Karen, Carraway, Martha Sue, MacGarvey, Nancy Chou, Withers, Crystal M., Sweeney, Timothy E., Piantadosi, Claude A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2011
Soggetti:
C. Critical Care
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040391/
https://ncbi.nlm.nih.gov/pubmed/20732986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200911-1709OC
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