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Peroxynitrite Induced Nitrative and Oxidative Modifications Alter Tau Filament Formation
Tau undergoes numerous post-translational modifications during the progression of Alzheimer’s disease (AD). Some of these changes accelerate tau aggregation, while others are inhibitory. AD-associated inflammation is thought to create oxygen and nitrogen radicals such as peroxynitrite (PN). In vitro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040256/ https://ncbi.nlm.nih.gov/pubmed/21210655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101735m |
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