Interferon-γ Regulates the Proliferation and Differentiation of Mesenchymal Stem Cells via Activation of Indoleamine 2,3 Dioxygenase (IDO)

The kynurenine pathway (KP) of tryptophan metabolism is linked to antimicrobial activity and modulation of immune responses but its role in stem cell biology is unknown. We show that human and mouse mesenchymal and neural stem cells (MSCs and NSCs) express the complete KP, including indoleamine 2,3...

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Autori principali: Croitoru-Lamoury, Juliana, Lamoury, Francois M. J., Caristo, Michael, Suzuki, Kazuo, Walker, David, Takikawa, Osamu, Taylor, Rosanne, Brew, Bruce J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040184/
https://ncbi.nlm.nih.gov/pubmed/21359206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014698
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