Extraadrenal steroid 21-hydroxylation is not mediated by P450c21.

The 21-hydroxylation of progesterone to deoxycorticosterone (DOC) and of 17-hydroxyprogesterone to 11-deoxycortisol in the human adrenal cortex is mediated by a single enzyme termed P450c21. Extraadrenal tissues can clear circulating progesterone and progesterone sulfate by 21-hydroxylation to DOC a...

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Publié dans:	J Clin Invest
Auteurs principaux:	Mellon, S H, Miller, W L
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1989
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2808702/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114325
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