Aberrant splicing and missense mutations cause steroid 21-hydroxylase [P-450(C21)] deficiency in humans: possible gene conversion products.
Four steroid 21-hydroxylase B [P-450(C21)B] genes (designated P.7, P.10-1, P.10-2, and P.3) from three P-450(C21)-deficient patients were isolated to analyze their structures and functions. Several base changes were observed in the sequences of the four P-450(C21)B genes as compared to that of the f...
Na minha lista:
| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1988
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282216/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.20.7486 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|