Extraadrenal steroid 21-hydroxylation is not mediated by P450c21.
The 21-hydroxylation of progesterone to deoxycorticosterone (DOC) and of 17-hydroxyprogesterone to 11-deoxycortisol in the human adrenal cortex is mediated by a single enzyme termed P450c21. Extraadrenal tissues can clear circulating progesterone and progesterone sulfate by 21-hydroxylation to DOC a...
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| Publicado no: | J Clin Invest |
|---|---|
| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304014/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2808702/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114325 |
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