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Identification of a Reduction Product of Aristolochic Acid: Implications for the Metabolic Activation of Carcinogenic Aristolochic Acid
Aristolochic acids are nephrotoxic and carcinogenic natural products that have been implicated both in the endemic nephropathy in the Balkans region and ailments caused by ingestion of herbal remedies. Aristolochic acids are metabolized to active intermediates that bind to DNA. In this study, reduct...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040066/ https://ncbi.nlm.nih.gov/pubmed/21141875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np100296y |
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