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Identification of a Reduction Product of Aristolochic Acid: Implications for the Metabolic Activation of Carcinogenic Aristolochic Acid

Aristolochic acids are nephrotoxic and carcinogenic natural products that have been implicated both in the endemic nephropathy in the Balkans region and ailments caused by ingestion of herbal remedies. Aristolochic acids are metabolized to active intermediates that bind to DNA. In this study, reduct...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Priestap, Horacio A., de los Santos, Carlos, Quirke, J. Martin E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040066/
https://ncbi.nlm.nih.gov/pubmed/21141875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np100296y
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