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Decreased bioactivity of the guanine nucleotide-binding protein that stimulates adenylate cyclase in hearts from cardiomyopathic Syrian hamsters.

We investigated regulation of cardiac adenylate cyclase in 29-d-old BIO 14.6 Syrian hamsters, which inherit cardiomyopathy as an autosomal recessive trait. Pharmacologic stimulation of adenylate cyclase in cardiac membranes with isoproterenol, fluoride ion, guanine nucleotide, forskolin, and mangano...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Kessler, P D, Cates, A E, Van Dop, C, Feldman, A M
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303976/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2544625/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114147
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