Decreased bioactivity of the guanine nucleotide-binding protein that stimulates adenylate cyclase in hearts from cardiomyopathic Syrian hamsters.

We investigated regulation of cardiac adenylate cyclase in 29-d-old BIO 14.6 Syrian hamsters, which inherit cardiomyopathy as an autosomal recessive trait. Pharmacologic stimulation of adenylate cyclase in cardiac membranes with isoproterenol, fluoride ion, guanine nucleotide, forskolin, and mangano...

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Pubblicato in:	J Clin Invest
Autori principali:	Kessler, P D, Cates, A E, Van Dop, C, Feldman, A M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2544625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114147
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