Antibacterial autophagy occurs at PtdIns(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase

Autophagy mediates the degradation of cytoplasmic components in eukaryotic cells and plays a key role in immunity. The mechanism of autophagosome formation is not clear. Here we examined two potential membrane sources for antibacterial autophagy: the ER and mitochondria. DFCP1, a marker of specializ...

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Autori principali: Huang, Ju, Birmingham, Cheryl L, Shahnazari, Shahab, Shiu, Jessica, Zheng, Yiyu T, Smith, Adam C, Campellone, Kenneth G, Do Heo, Won, Gruenheid, Samantha, Meyer, Tobias, Welch, Matthew D, Ktistakis, Nicholas T, Kim, Peter K, Klionsky, Daniel J, Brumell, John H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
Soggetti:
Basic Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039730/
https://ncbi.nlm.nih.gov/pubmed/20980813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.1.13840
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