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Antibacterial autophagy occurs at PtdIns(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase

Autophagy mediates the degradation of cytoplasmic components in eukaryotic cells and plays a key role in immunity. The mechanism of autophagosome formation is not clear. Here we examined two potential membrane sources for antibacterial autophagy: the ER and mitochondria. DFCP1, a marker of specializ...

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Autors principals: Huang, Ju, Birmingham, Cheryl L, Shahnazari, Shahab, Shiu, Jessica, Zheng, Yiyu T, Smith, Adam C, Campellone, Kenneth G, Do Heo, Won, Gruenheid, Samantha, Meyer, Tobias, Welch, Matthew D, Ktistakis, Nicholas T, Kim, Peter K, Klionsky, Daniel J, Brumell, John H
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039730/
https://ncbi.nlm.nih.gov/pubmed/20980813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.1.13840
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