ARRB1-Mediated Regulation of E2F Target Genes in Nicotine-Induced Growth of Lung Tumors

BACKGROUND: Nicotine induces the proliferation of non–small cell lung cancer (NSCLC) cells via nicotinic acetylcholine receptors and the arrestin, β1 (ARRB1) protein. However, whether ARRB1 translocates to the nucleus upon nicotinic acetylcholine receptor activation and how it regulates growth of hu...

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Main Authors: Dasgupta, Piyali, Rizwani, Wasia, Pillai, Smitha, Davis, Rebecca, Banerjee, Sarmistha, Hug, Kevin, Lloyd, Mark, Coppola, Domenico, Haura, Eric, Chellappan, Srikumar P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039728/
https://ncbi.nlm.nih.gov/pubmed/21212384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djq541
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