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Mammalian Lysine Histone Demethylase KDM2A Regulates E2F1-Mediated Gene Transcription in Breast Cancer Cells

It is established that histone modifications like acetylation, methylation, phosphorylation and ubiquitination affect chromatin structure and modulate gene expression. Lysine methylation/demethylation on Histone H3 and H4 is known to affect transcription and is mediated by histone methyl transferase...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rizwani, Wasia, Schaal, Courtney, Kunigal, Sateesh, Coppola, Domenico, Chellappan, Srikumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100745/
https://ncbi.nlm.nih.gov/pubmed/25029110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100888
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