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The Bcl-2-Beclin 1 interaction in (-)-gossypol-induced autophagy versus apoptosis in prostate cancer cells

Bcl-2 is a key dual regulator of autophagy and apoptosis, but how the level of Bcl-2 influences the cellular decision between autophagy and apoptosis is unclear. The natural BH3-mimetic (-)-gossypol preferentially induces autophagy in androgen-independent (AI) prostate cancer cells that have high le...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lian, Jiqin, Karnak, David, Xu, Liang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039723/
https://ncbi.nlm.nih.gov/pubmed/20930561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.8.13549
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