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BCL2L11/BIM: A novel molecular link between autophagy and apoptosis
In response to toxic stimuli, BCL2L11 (also known as BIM), a BH3-only protein, is released from its interaction with dynein light chain 1 (DYNLL1 also known as LC8) and can induce apoptosis by inactivating anti-apoptotic BCL2 proteins and by activating BAX-BAK1. Recently, we discovered that BCL2L11...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3542209/ https://ncbi.nlm.nih.gov/pubmed/23064249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22399 |
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