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BCL2L11/BIM: A novel molecular link between autophagy and apoptosis

In response to toxic stimuli, BCL2L11 (also known as BIM), a BH3-only protein, is released from its interaction with dynein light chain 1 (DYNLL1 also known as LC8) and can induce apoptosis by inactivating anti-apoptotic BCL2 proteins and by activating BAX-BAK1. Recently, we discovered that BCL2L11...

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Autors principals: Luo, Shouqing, Rubinsztein, David C.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542209/
https://ncbi.nlm.nih.gov/pubmed/23064249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22399
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