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Three point mutations in the factor IX genes of five hemophilia B patients. Identification strategy using localization by altered epitopes in their hemophilic proteins.

In five patients with hemophilia B and detectable Factor IX antigen, altered reactivity to a specific polyclonal antibody fraction or monoclonal anti-Factor IX antibodies was noted. Amplification of selected portions of their Factor IX genes by polymerase chain reaction allowed rapid identification...

詳細記述

保存先:
書誌詳細
主要な著者: Chen, S H, Thompson, A R, Zhang, M, Scott, C R
フォーマット: Artigo
言語:Inglês
出版事項: 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC303960/
https://ncbi.nlm.nih.gov/pubmed/2472424
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