Mesenteric lymph node cells from neonates present a prominent IL-12 response to CpG oligodeoxynucleotide via an IL-15 feedback loop of amplification

At birth, the immune system is still in development making neonates more susceptible to infections. The recognition of microbial ligands is a key step in the initiation of immune responses. It can be mimicked to stimulate the immune system by the use of synthetic ligands recognising pattern recognit...

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Bibliographic Details
Main Authors:	Ferret-Bernard, Stéphanie, Lacroix-Lamandé, Sonia, Remot, Aude, Metton, Coralie, Bernardet, Nelly, Charley, Bernard, Drouet, Françoise, Laurent, Fabrice
Format:	Artigo
Language:	Inglês
Published:	BioMed Central 2011
Subjects:	Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3039596/ https://ncbi.nlm.nih.gov/pubmed/21314903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9716-42-19
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Mesenteric lymph node cells from neonates present a prominent IL-12 response to CpG oligodeoxynucleotide via an IL-15 feedback loop of amplification

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