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Crystal Structures of a Cysteine-modified Mutant in Loop D of Acetylcholine-binding Protein

Covalent modification of α7 W55C nicotinic acetylcholine receptors (nAChR) with the cysteine-modifying reagent [2-(trimethylammonium)ethyl] methanethiosulfonate (MTSET(+)) produces receptors that are unresponsive to acetylcholine, whereas methyl methanethiolsulfonate (MMTS) produces enhanced acetylc...

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Detalhes bibliográficos
Main Authors: Brams, Marijke, Gay, Elaine A., Sáez, José Colón, Guskov, Albert, van Elk, René, van der Schors, Roel C., Peigneur, Steve, Tytgat, Jan, Strelkov, Sergei V., Smit, August B., Yakel, Jerrel L., Ulens, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039400/
https://ncbi.nlm.nih.gov/pubmed/21115477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.188730
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