Nrf2 Induces Interleukin-6 (IL-6) Expression via an Antioxidant Response Element within the IL-6 Promoter

IL-6 gene expression is controlled by a promoter region containing multiple regulatory elements such as NF-κB, NF-IL6, CRE, GRE, and TRE. In this study, we demonstrated that TRE, found within the IL-6 promoter, is embedded in a functional antioxidant response element (ARE) matching an entire ARE con...

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Bibliographic Details
Main Authors: Wruck, Christoph Jan, Streetz, Konrad, Pavic, Goran, Götz, Mario E., Tohidnezhad, Mersedeh, Brandenburg, Lars-Ove, Varoga, Deike, Eickelberg, Oliver, Herdegen, Thomas, Trautwein, Christian, Cha, Kaimin, Kan, Yuet Wai, Pufe, Thomas
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039356/
https://ncbi.nlm.nih.gov/pubmed/21127061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.162008
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