Sulforaphane has opposing effects on TNF-alpha stimulated and unstimulated synoviocytes

INTRODUCTION: Rheumatoid arthritis (RA) is characterized by progressive inflammation associated with rampantly proliferating synoviocytes and joint destruction due to oxidative stress. Recently, we described nuclear factor erythroid 2-related factor 2 (Nrf2) as a major requirement for limiting carti...

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Detalhes bibliográficos
Main Authors: Fragoulis, Athanassios, Laufs, Jendrik, Müller, Susanna, Soppa, Ulf, Siegl, Stephanie, Reiss, Lucy Kathleen, Tohidnezhad, Mersedeh, Rosen, Christian, Tenbrock, Klaus, Varoga, Deike, Lippross, Sebastian, Pufe, Thomas, Wruck, Christoph Jan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580531/
https://ncbi.nlm.nih.gov/pubmed/23072510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4059
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