Hepatocytes express the antimicrobial peptide HBD-2 after multiple trauma: an experimental study in human and mice

BACKGROUND: Human-beta defensins (HBD) belong to the family of acute phase peptides and hold a broad antimicrobial spectrum that includes gram-positive and gram-negative bacteria. HBD are up-regulated after severe injuries but the source of posttraumatic HBD expression has not been focused on before...

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Detalhes bibliográficos
Publicado no:BMC Musculoskelet Disord
Main Authors: Fitschen-Oestern, Stefanie, Weuster, Matthias, Lippross, Sebastian, Behrendt, Peter, Fuchs, Sabine, Pufe, Thomas, Tohidnezhad, Mersedeh, Bayer, Andreas, Seekamp, Andreas, Varoga, Deike, Klüter, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341361/
https://ncbi.nlm.nih.gov/pubmed/28270138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-017-1458-8
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