Nrf2 Ameliorates DDC-Induced Sclerosing Cholangitis and Biliary Fibrosis and Improves the Regenerative Capacity of the Liver

The Nrf2 pathway protects against oxidative stress and induces regeneration of various tissues. Here, we investigated whether Nrf2 protects from sclerosing cholangitis and biliary fibrosis and simultaneously induces liver regeneration. Diet containing 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC)...

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Bibliografiset tiedot
Julkaisussa:Toxicol Sci
Päätekijät: Fragoulis, Athanassios, Schenkel, Julia, Herzog, Miriam, Schellenberg, Tim, Jahr, Holger, Pufe, Thomas, Trautwein, Christian, Kensler, Thomas W, Streetz, Konrad L, Wruck, Christoph Jan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2019
Aiheet:
Nrf2 REDUCES FIBROSIS AND ENHANCES REGENERATION IN LIVER
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542338/
https://ncbi.nlm.nih.gov/pubmed/30825315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfz055
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