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Adenylate Kinase 2 Links Mitochondrial Energy Metabolism to the Induction of the Unfolded Protein Response

The unfolded protein response (UPR) is a homeostatic signaling mechanism that balances the protein folding capacity of the endoplasmic reticulum (ER) with the secretory protein load of the cell. ER protein folding capacity is dependent on the abundance of chaperones, which is increased in response t...

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Detalles Bibliográficos
Main Authors: Burkart, Alison, Shi, Xiarong, Chouinard, My, Corvera, Silvia
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039340/
https://ncbi.nlm.nih.gov/pubmed/20876536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.134106
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