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Characterization of the B6.61 polymerase ribozyme accessory domain

The “RNA world” hypothesis rests on the assumption that RNA polymerase ribozymes can replicate RNA without the use of protein. In the laboratory, in vitro selection has been used to create primitive versions of such polymerases. The best variant to date is a ribozyme called B6.61 that can extend a R...

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Autors principals: Wang, Qing S., Cheng, Leslie K.L., Unrau, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039146/
https://ncbi.nlm.nih.gov/pubmed/21224380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2495011
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