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In vitro characterization of 6S RNA release-defective mutants uncovers features of pRNA-dependent release from RNA polymerase in E. coli

6S RNA is a noncoding RNA that inhibits bacterial transcription by sequestering RNA polymerase holoenzyme (Eσ(70)) in low-nutrient conditions. This transcriptional block can be relieved by the synthesis of a short product RNA (pRNA) using the 6S RNA as a template. Here, we selected a range of 6S RNA...

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Detalles Bibliográficos
Main Authors: Oviedo Ovando, Mariana, Shephard, Lindsay, Unrau, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988568/
https://ncbi.nlm.nih.gov/pubmed/24681966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.036343.112
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