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Hearing and vestibular deficits in the Coch(−/−) null mouse model: comparison to the Coch(G88E/G88E) mouse and to DFNA9 hearing and balance disorder
Two mouse models, the Coch(G88E/G88E) or “knock-in” and the Coch(−/−) or “knock-out” (Coch null), have been developed to study the human late-onset, progressive, sensorineural hearing loss and vestibular dysfunction known as DFNA9. This disorder results from missense and in-frame deletion mutations...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039082/ https://ncbi.nlm.nih.gov/pubmed/21073934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2010.11.002 |
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