A targeted Coch missense mutation: a knock-in mouse model for DFNA9 late-onset hearing loss and vestibular dysfunction

Mutations in COCH (coagulation factor C homology) are etiologic for the late-onset, progressive, sensorineural hearing loss and vestibular dysfunction known as DFNA9. We introduced the G88E mutation by gene targeting into the mouse and have created a Coch(G88E/G88E) mouse model for the study of DFNA...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Robertson, Nahid G., Jones, Sherri M., Sivakumaran, Theru A., Giersch, Anne B.S., Jurado, Sara A., Call, Linda M., Miller, Constance E., Maison, Stéphane F., Liberman, M. Charles, Morton, Cynthia C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566528/
https://ncbi.nlm.nih.gov/pubmed/18697796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn236
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados