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Error and Error Mitigation in Low-Coverage Genome Assemblies

The recent release of twenty-two new genome sequences has dramatically increased the data available for mammalian comparative genomics, but twenty of these new sequences are currently limited to ∼2× coverage. Here we examine the extent of sequencing error in these 2× assemblies, and its potential im...

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Detalhes bibliográficos
Main Authors: Hubisz, Melissa J., Lin, Michael F., Kellis, Manolis, Siepel, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038916/
https://ncbi.nlm.nih.gov/pubmed/21340033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017034
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