D-Cbl Binding to Drk Leads to Dose-Dependent Down-Regulation of EGFR Signaling and Increases Receptor-Ligand Endocytosis

Proper control of Epidermal Growth Factor Receptor (EGFR) signaling is critical for normal development and regulated cell behaviors. Abnormal EGFR signaling is associated with tumorigenic process of various cancers. Complicated feedback networks control EGFR signaling through ligand production, and...

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Bibliografske podrobnosti
Main Authors: Wang, Pei-Yu, Pai, Li-Mei
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038869/
https://ncbi.nlm.nih.gov/pubmed/21340027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017097
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