Determinants of TRPV4 Activity following Selective Activation by Small Molecule Agonist GSK1016790A

TRPV4 (Transient Receptor Potential Vanilloid 4) channels are activated by a wide range of stimuli, including hypotonic stress, non-noxious heat and mechanical stress and some small molecule agonists (e.g. phorbol ester 4α-PDD). GSK1016790A (GSK101) is a recently discovered specific small molecule a...

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Detalhes bibliográficos
Main Authors: Jin, Min, Wu, Zizhen, Chen, Ling, Jaimes, Jose, Collins, Diana, Walters, Edgar T., O'Neil, Roger G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038856/
https://ncbi.nlm.nih.gov/pubmed/21339821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016713
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