The TRPV4 Agonist GSK1016790A Regulates the Membrane Expression of TRPV4 Channels

TRPV4 is a non-selective cation channel that tunes the function of different tissues including the vascular endothelium, lung, chondrocytes, and neurons. GSK1016790A is the selective and potent agonist of TRPV4 and a pharmacological tool that is used to study the TRPV4 physiological function in vitr...

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Vydáno v:Front Pharmacol
Hlavní autoři: Baratchi, Sara, Keov, Peter, Darby, William G., Lai, Austin, Khoshmanesh, Khashayar, Thurgood, Peter, Vahidi, Parisa, Ejendal, Karin, McIntyre, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351496/
https://ncbi.nlm.nih.gov/pubmed/30728775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00006
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