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Optical Recording Reveals Novel Properties of GSK1016790A-Induced Vanilloid Transient Receptor Potential Channel TRPV4 Activity in Primary Human Endothelial Cells

Critical functions of the vascular endothelium are regulated by changes in intracellular [Ca(2+)]. Endothelial dysfunction is tightly associated with cardiovascular disease, and improved understanding of Ca(2+) entry pathways in these cells will have a significant impact on human health. However, mu...

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Detalhes bibliográficos
Main Authors: Sullivan, Michelle N., Francis, Michael, Pitts, Natalie L., Taylor, Mark S., Earley, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422704/
https://ncbi.nlm.nih.gov/pubmed/22689561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.078584
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