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Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome

Among the hallmark phenotypes reported in individuals with fragile X syndrome (FXS) are deficits in attentional function, inhibitory control, and cognitive flexibility, a set of cognitive skills thought to be associated with the prefrontal cortex (PFC). However, despite substantial clinical research...

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Autores principales: Krueger, Dilja D., Osterweil, Emily K., Chen, Stephanie P., Tye, Lynne D., Bear, Mark F.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038768/
https://ncbi.nlm.nih.gov/pubmed/21262808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013855108
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