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Astrocytic contributions to synaptic and learning abnormalities in a mouse model of Fragile X Syndrome
BACKGROUND: Fragile X Syndrome (FXS) is the most common type of mental retardation attributable to a single-gene mutation. It is caused by FMR1 gene silencing and the consequent loss of its protein product, Fragile X Mental Retardation Protein (FMRP). Fmr1 global knock out (KO) mice recapitulate man...
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| Publicado no: | Biol Psychiatry |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5348290/ https://ncbi.nlm.nih.gov/pubmed/27865451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.08.036 |
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