Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A

Improved protein-based vaccines should facilitate the goal of effective vaccines against HIV and other pathogens. With respect to T cells, the efficiency of immunization, or “immunogenicity,” is improved by targeting vaccine proteins to maturing dendritic cells (DCs) within mAbs to DC receptors. Her...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Idoyaga, Juliana, Lubkin, Ashira, Fiorese, Christopher, Lahoud, Mireille H., Caminschi, Irina, Huang, Yaoxing, Rodriguez, Anthony, Clausen, Björn E., Park, Chae Gyu, Trumpfheller, Christine, Steinman, Ralph M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038758/
https://ncbi.nlm.nih.gov/pubmed/21262813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1019547108
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk