Llwytho...

Cell Surface Binding and Internalization of Aβ Modulated by Degree of Aggregation

The amyloid peptides, Aβ40 and Aβ42, are generated through endoproteolytic cleavage of the amyloid precursor protein. Here we have developed a model to investigate the interaction of living cells with various forms of aggregated Aβ40/42. After incubation at endosomal pH 6, we observed a variety of A...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bateman, David A., Chakrabartty, Avijit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE-Hindawi Access to Research 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038693/
https://ncbi.nlm.nih.gov/pubmed/21331340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/962352
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