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Two Distinct Conformations of Aβ Aggregates on the Surface of Living PC12 Cells

Aβ42 has been found to associate rapidly to neuronal cells and is the primary constituent of senile plaques. In this study we monitored the aggregation of Aβ42 with living PC12 cells. Using photobleaching Förster resonance energy transfer, we observed one set of aggregates that displayed colocalizat...

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Detalhes bibliográficos
Main Authors: Bateman, David A., Chakrabartty, Avijit
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712147/
https://ncbi.nlm.nih.gov/pubmed/19450496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.056
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