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Two Distinct Conformations of Aβ Aggregates on the Surface of Living PC12 Cells

Aβ42 has been found to associate rapidly to neuronal cells and is the primary constituent of senile plaques. In this study we monitored the aggregation of Aβ42 with living PC12 cells. Using photobleaching Förster resonance energy transfer, we observed one set of aggregates that displayed colocalizat...

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Bibliografiske detaljer
Main Authors: Bateman, David A., Chakrabartty, Avijit
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712147/
https://ncbi.nlm.nih.gov/pubmed/19450496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.056
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