Mutagenesis of the peptidyltransferase center of 23S rRNA: the invariant U2449 is dispensable

U2449 is one of many invariant residues in the central loop of domain V of 23S rRNA, a region that constitutes part of the peptidyltransferase center of the ribosome. In Escherichia coli, this U is post-transcriptionally modified to dihydrouridine (D) and is the only D modification found in E.coli r...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	O’Connor, Michael, Lee, Wyan-Ching Mimi, Mankad, Anuj, Squires, Catherine L., Dahlberg, Albert E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30386/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.3.710
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