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Mutagenesis of the peptidyltransferase center of 23S rRNA: the invariant U2449 is dispensable

U2449 is one of many invariant residues in the central loop of domain V of 23S rRNA, a region that constitutes part of the peptidyltransferase center of the ribosome. In Escherichia coli, this U is post-transcriptionally modified to dihydrouridine (D) and is the only D modification found in E.coli r...

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Bibliografische gegevens
Hoofdauteurs: O’Connor, Michael, Lee, Wyan-Ching Mimi, Mankad, Anuj, Squires, Catherine L., Dahlberg, Albert E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC30386/
https://ncbi.nlm.nih.gov/pubmed/11160893
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