Common epitope in human immunodeficiency virus (HIV) I-GP41 and HLA class II elicits immunosuppressive autoantibodies capable of contributing to immune dysfunction in HIV I-infected individuals.

We previously reported the identification of highly conserved homologous regions located in the carboxy terminus of the HIV I gp41-envelope (aa 837-844), and the amino-terminal of the beta chain of all human HLA class II antigens (aa 19-25). Murine monoclonal antibodies, raised against synthetic pep...

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Bibliografske podrobnosti
Main Authors: Golding, H, Shearer, G M, Hillman, K, Lucas, P, Manischewitz, J, Zajac, R A, Clerici, M, Gress, R E, Boswell, R N, Golding, B
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC303840/
https://ncbi.nlm.nih.gov/pubmed/2467924
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