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Decreased Diacylglycerol Metabolism Enhances ERK Activation and Augments CD8(+) T Cell Functional Responses
Modulation of T cell receptor signal transduction in CD8(+) T cells represents a novel strategy toward enhancing the immune response to tumor. Recently, levels of guanine exchange factors, RasGRP and SOS, within T cells have been shown to represent a key determinant in the regulation of the analog t...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037638/ https://ncbi.nlm.nih.gov/pubmed/21138839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.171884 |
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