The Tumor Suppressor hTid1 Inhibits STAT5b Activity via Functional Interaction

STAT5a and -5b (signal transducers and activators of transcription 5a and 5b) proteins play an essential role in hematopoietic cell proliferation and survival and are frequently constitutively active in hematologic neoplasms and solid tumors. Because STAT5a and STAT5b differ mainly in the carboxyl-t...

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Bibliographic Details
Main Authors: Dhennin-Duthille, Isabelle, Nyga, Rémy, Yahiaoui, Saliha, Gouilleux-Gruart, Valérie, Régnier, Aline, Lassoued, Kaïss, Gouilleux, Fabrice
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037615/
https://ncbi.nlm.nih.gov/pubmed/21106534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.155903
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