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Linked Thioredoxin-Glutathione Systems in Platyhelminth Parasites: ALTERNATIVE PATHWAYS FOR GLUTATHIONE REDUCTION AND DEGLUTATHIONYLATION

In most organisms, thioredoxin (Trx) and/or glutathione (GSH) systems are essential for redox homeostasis and deoxyribonucleotide synthesis. Platyhelminth parasites have a unique and simplified thiol-based redox system, in which the selenoprotein thioredoxin-glutathione reductase (TGR), a fusion of...

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Bibliographische Detailangaben
Hauptverfasser: Bonilla, Mariana, Denicola, Ana, Marino, Stefano M., Gladyshev, Vadim N., Salinas, Gustavo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037608/
https://ncbi.nlm.nih.gov/pubmed/21051543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.170761
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